Model No.︰CAS 73-78-9
Brand Name︰MU LEI (WUHAN)
Country of Origin︰China
Unit Price︰US $ 30 / KG
Minimum Order︰1 KG
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hcl basic information:
Boiling Point | 350.8ºC at 760 mmHg |
---|---|
Melting Point | 80-82°C |
Molecular Formula | C14H23ClN2O |
Molecular Weight | 270.798 |
Flash Point | 166ºC |
Exact Mass | 270.149902 |
PSA | 32.34000 |
LogP | 3.45870 |
Storage condition |
Refrigerator
is a common local anesthetic and antiarrhythmic drug. is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. , the first amino amide–type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself. is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than but also is a less potent sodium channel blocker. The elimination half-life of is approximately 90–120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes). |
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